学位：工学博士

职称/职务：讲师

E-mail：18737605989@163.com

研究方向：益生菌资源挖掘与功效评价

2026年6月获天津科技大学轻工技术与工程专业工学博士学位，2026年8月来校工作。主讲《食品机械与设备》。

主持或参加科研项目（课题）情况:

1.国家自然科学基金联合基金项目，黑龙江道地药食同源发酵类中药活性成分生物转化及基于肠道微生态调节的功效机制研究，参与，2022.09-2024.12.

2. 青海省人才项目，青海省高端创新创业人才-柔性引进领军人才，参与，2023.04-2026.06.

3. 技术开发项目，益生菌/后生元功能评价，参与，2023.07-2024.06

4. 青海省人才项目，青藏高原传统乳制品安全控制与发酵剂研制关键技术，参与，2019.09-2022.09

近年来发表的代表性论文：

1.Zhang X,Wang Xin-Ran, Gai Sai Lun, et al. Gut microbiota reshaped by exercise improved glycolipid metabolism in obese mice via increasing the production of medium and long chain fatty acids: a multi-omics study.Journal of Nutritional Biochemistry, 2026.

2.Zhang X, Yin S, Quan X Y, et al. Optimising conditions for extracellular vesicle production in Lacticaseibacillus paracasei LH23 via response surface methodology and exploring their stability, safety and anti-inflammatory capacity. Probiotics and Antimicrobial Proteins. 2025. (2区)

3.Zhang X, Jia, Lina, Ma Q, et al. Astragalus Polysaccharide Modulates the Gut Microbiota and Metabolites of Patients with Type 2 Diabetes in an In Vitro Fermentation Model. Nutrients, 2024, 16(11): 1698. (2区)

4.Zhang X, Ma Q, Jia Lina，et al. Effects of in vitro fermentation of Atractylodes chinensis (DC.) Koidz. polysaccharide on fecal microbiota and metabolites in patients with type 2 diabetes mellitus. International Journal of Biological Macromolecules: Structure, Function and Interactions, 2023, 253(Pt 3): 126860. (TOP).

5.Zhang X, Yang J, Zhang C, et al. Effects of Lactobacillus fermentum HY01 on the quality characteristics and storage stability of yak yogurt. Journal of dairy science, 2022. 105(3): 2025-2037. (TOP)

6.Zhang X, Yang J, Zhang C, et al. Postbiotics derived from Lactobacillus plantarum 1.0386 Ameliorates lipopolysaccharide-induced tight junction injury via MicroRNA-200c-3p Mediated Activation of MLCK-MLC Pathway in Caco-2 Cells. Food & function, 2022, 13(21):11008-11020. (TOP)

7.Zhang X, Li Y, Jia jie Yang, et al. The effects of inulin combined with galacto-oligosaccharide on the various properties of synbiotic soy cheese containing Lactobacillus acidophilus KLDS 1.0738. Quality Assurance and Safety of Crops & Foods. 2020, 12 (3): 46–54.

8.李艾黎，张欣，李颖, et al. miRNA参与益生菌调节肠道屏障功能的研究进展.食品科学，2019。

专利

1. 一种提高乳酸菌胞外囊泡产率的方法。发明人：王楠、张欣、王雨卉、权雪莹和韩雨晴。申请人：天津科技大学。2025，专利号：CN120888445A)。